China Eastern Airlines (MU, Shanghai Hongqiao) ended A340-600 commercial operations on Sunday, May 3 when B-6055 (cn 586) completed its last revenue flight from Tokyo Narita to Shanghai Pudong. The quadjet was not only the last of the type in service with China Eastern, but the last in service in China as a whole. The aircraft was used on flights from Shnaghai to Tokyo as well as to Singapore Changi and Toronto Pearson.

As with its A340-500 sister type, the number of commercial operators of the A340-600 is dwindling fast with ships in service with Lufthansa (LH, Frankfurt International), Iberia (IB, Madrid Barajas), Virgin Atlantic (VS, London Heathrow), South African Airways (SA, Johannesburg O.R. Tambo), Etihad Airways (EY, Abu Dhabi International), Qatar Airways (QR, Doha Hamad International), AZAL Azerbaijan Airlines (J2, Baku Heydar Aliev International) and Global Jet Luxembourg (SVW, Luxembourg).